lactate dehydrogenase — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T15435	GSK2837808A		Dehydrogenase
	GSK2837808A is a potent and selective inhibitor of lactate dehydrogenase A (LDHA) (IC50s: 1.9 and 14 nM for LDHA and LDHB, respectively).		Dehydrogenase
T5705	Glomeratose A		Dehydrogenase
	Glomeratose A is a lactate dehydrogenase inhibitor.		Dehydrogenase
T11829	LDH-IN-1		Dehydrogenase
	LDH-IN-1 is a pyrazole-based human lactate dehydrogenase (LDH) inhibitor(IC50s of 32 and 27 nM for LDHA and LDHB, respectively).		Dehydrogenase
T11546	HDHODH-IN-1		Dehydrogenase
	hDHODH-IN-1 is a human dihydroorotate dehydrogenase (hDHODH) inhibitor with an anti-inflammatory effect.		Dehydrogenase
T22336	Galloflavin		Dehydrogenase
	Galloflavin inhibits both the A and B isoforms of lactate dehydrogenase with Ki of 5.46 µM and 15.06 µM, respectively. Galloflavin is also a potential anticancer agent.		Dehydrogenase
T4295	(R)-GNE-140	GNE-140	Dehydrogenase
	(R)-GNE-140 (GNE-140) is an effective LDHA/LDHB inhibitor (IC50s: 3/5 nM) and is 18-fold more potent than S enantiomer.		Dehydrogenase
T76116	L-Lactate dehydrogenase
	L-Lactate dehydrogenase, a redox enzyme, catalyzes the in vivo reduction of pyruvate to L-lactate with absolute enantiospecificity by utilizing NADH [1].
T76146	D-Lactate dehydrogenase
	D-Lactate dehydrogenase (D-LDH), an oxidoreductase, catalyzes the oxidation of D-lactate to pyruvate leveraging NAD+ or NADP+ as acceptors and acting on the donor CH-OH group. Predominantly found in bacteria and fungi, i...
T12438	PfDHODH-IN-1		Dehydrogenase , Parasite
	PfDHODH-IN-1 is an analogue of the active Leflunomide metabolite, has antimalarial activity.		Dehydrogenase , Parasite
T7964	Isomalt	Palatinitol,Palatinit	Others , Dehydrogenase
	Isomalt (Palatinitol) is a mixture of 1,6-mannitol glucopyranoside and 1,6-sorbitol glucopyranoside		Others , Dehydrogenase
T5S0620	3-Dehydrotrametenolic acid	Dehydrotrametenolic acid	Apoptosis , Others , Dehydrogenase
	1. 3-Dehydrotrametenolic acid can be a potential anticancer agent against H-ras transformed tumor. 2. Dehydrotrametenolic acid is a promising candidate for a new type of insulin-sensitizing drug.		Apoptosis , Others , Dehydrogenase
T3175	LDHA-IN-4	AZ 33,AZ-33,LDHA Inhibitor,AZ33	Dehydrogenase
	LDHA-IN-4 (AZ33) is an LDHA inhibitor. Binding affinity to 6-His-tagged human LDHA (2 to 322 amino acid residue) expressed in Escherichia coli BL21 (DE3) cells by SPR analysis with an active value of 0.093 μM.		Dehydrogenase
T5325	Nifurtimox	BAY-2502,BAY-A-2502	Dehydrogenase , Parasite
	Nifurtimox (BAY-A-2502) is an antiprotozoal agent (IC50s = 9.91, 12.28, and 10.44 μM against Taluahuén, LQ, and Brener strains of T. cruzi- epimastigotes, respectively).		Dehydrogenase , Parasite
T4738	Sodium 2-hydroxybutanoate	2-Hydroxybutyric acid sodium salt,DL-2-Hydroxybutyric Acid Sodium Salt,alpha-hydroxybutyrate,SODIUM 2-HYDROXYBUTYRATE	Others , Endogenous Metabolite
	Sodium 2-hydroxybutanoate (alpha-hydroxybutyrate) is formed as a by-product of the formation of alpha-ketobutyrate via a reaction catalyzed by lactate dehydrogenase (LDH) or alpha-hydroxybutyrate dehydrogenase (alphaHBDH...		Others , Endogenous Metabolite
T64345	4-(Dimethylamino)phenol		Others
	4-(Dimethylamino)phenol enhances extracellular lactate dehydrogenase (LDH) levels without significant effects on gluconeogenesis. Only when the membrane becomes permeable to LDH does 4-(Dimethylamino)phenol reduce ATP co...		Others
T2S2211	Tenuifoliside C		Dehydrogenase
	Tenuifoliside C, isolated from polygala tenuifolia willd, is a target lactate dehydrogenase inhibitor. It significantly inhibits chlorzoxazone 6-hydroxylation catalyzed by CYP2E1[1].		Dehydrogenase
TN1829	Kakkalide		Dehydrogenase
	Kakkalide is a potent lactate dehydrogenase (LDH) inhibitor, it has anti-inflammatory effects.		Dehydrogenase
T5S2195	Sibiricose A5		Dehydrogenase
	Sibiricose A5 is a lactate dehydrogenase inhibitor, it displays antidepressant-like, and antioxidant actions. Sibiricose A5 can protect PC12 cells damage induced by P. tenuifolia.		Dehydrogenase
T4103	(L)-Sodium lactate	Sodium L-Lactate	Others
	(L)-Sodium lactate (Sodium L-Lactate) is produced from pyruvate by the enzyme Lactate Dehydrogenase. Lactate production occurs during anaerobic glycolysis or in proliferatively active cells. L-Lactic Acid occurs in small...		Others
T77579	JC2-11		IL Receptor , Dehydrogenase , ROS , Caspase , NOD-like Receptor (NLR) , AIM2
	JC2-11 is an inhibitory compound for inflammation.JC2-11 inhibits the recruitment domain-containing proteins NLRC 4, atypical in melanoma 2 (AIM 2) and atypical (NC) inflammatory vesicles by disrupting reactive oxygen sp...